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Experiences with
Panobinostat
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Ketogenic diet alters the epigenetic and immune landscape of prostate cancer to overcome resistance to immune checkpoint blockade therapy.
HDACi = histone deacetylase inhibitor [To date, four HDAC inhibitors, Vorinostat, Romidepsin,
Panobinostat
, and Belinostat, have been approved by the United States Food and Drug Administration.
HDACi = histone deacetylase inhibitor [To date, four HDAC inhibitors, Vorinostat, Romidepsin,
Panobinostat
, and Belinostat, have been approved by the United States Food and Drug Administration.
cigafred
in
Fight Prostate Cancer
29 days ago
Strategies to Re-Sensitize Castration-Resistant Prostate Cancer to Antiandrogen Therapy
Some examples are: bipolar androgen therapy (BAT) and drugs such as indomethacin, niclosamide, lapatinib,
panobinostat
, clomipramine, metformin, and antisense oligonucleotides.
Some examples are: bipolar androgen therapy (BAT) and drugs such as indomethacin, niclosamide, lapatinib,
panobinostat
, clomipramine, metformin, and antisense oligonucleotides.
pca2004
in
Fight Prostate Cancer
1 year ago
MPN News for treatment primary myelofibrosis, post-PVMF, Post ET-MF and Primary myelofibrosis
The investigators concluded that the combination of
panobinostat
and ruxolitinib was feasible in the patient population. Multiple combination trials were initiated during the time period that this trial was launched, limiting patient enrollment for this trial, wrote the authors.
The investigators concluded that the combination of
panobinostat
and ruxolitinib was feasible in the patient population. Multiple combination trials were initiated during the time period that this trial was launched, limiting patient enrollment for this trial, wrote the authors.
mammared
in
MPN Voice
4 years ago
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Epigenetic Therapy with Panobinostat Combined with Bicalutamide Rechallenge in Castration-Resistant Prostate Cancer.
CONCLUSIONS: The 40 mg
panobinostat
/bicalutamide regimen increased rPF survival in CRPC patients resistant to 2ndLAARx.
Panobinostat
toxicity was tolerable with dose reductions.
CONCLUSIONS: The 40 mg
panobinostat
/bicalutamide regimen increased rPF survival in CRPC patients resistant to 2ndLAARx.
Panobinostat
toxicity was tolerable with dose reductions.
JLS1
in
Advanced Prostate Cancer
4 years ago
Panobinostat.
A phase I trial had a 3 × 3
panobinostat
dose-escalation design. The phase II study randomized 55 patients to
panobinostat
40 mg (A arm) or 20 mg (B arm) triweekly ×2 weeks with bicalutamide 50 mg/day in 3-week cycles.
A phase I trial had a 3 × 3
panobinostat
dose-escalation design. The phase II study randomized 55 patients to
panobinostat
40 mg (A arm) or 20 mg (B arm) triweekly ×2 weeks with bicalutamide 50 mg/day in 3-week cycles.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Foods/Supplements-Vitamins: Apigenin
e.g. one paired Casodex with
Panobinostat
(a histone deacetylase inhibitor). Back to [5]: "Apigenin treatment resulted in the inhibition of class I histone deacetylases and HDAC1 protein expression ...
e.g. one paired Casodex with
Panobinostat
(a histone deacetylase inhibitor). Back to [5]: "Apigenin treatment resulted in the inhibition of class I histone deacetylases and HDAC1 protein expression ...
pjoshea13
in
Advanced Prostate Cancer
8 years ago
Looking for panobinostat patient
We are looking to speak with a myeloma patient who has been prescribed
panobinostat
as part of their treatment so that others can better understand their story. If you know someone, please message me. Thanks! Andrew Schorr
We are looking to speak with a myeloma patient who has been prescribed
panobinostat
as part of their treatment so that others can better understand their story. If you know someone, please message me. Thanks! Andrew Schorr
andrewschorr
in
Myeloma America Support
9 years ago
Introducing Myself
Currently, I am in a clinical trial taking
Panobinostat
, MLN9708 and Dex. We hope to get my numbers down so that I can proceed to a RIC Allogeneic stem cell transplant.
Currently, I am in a clinical trial taking
Panobinostat
, MLN9708 and Dex. We hope to get my numbers down so that I can proceed to a RIC Allogeneic stem cell transplant.
KimMarr
in
Myeloma America Support
10 years ago
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