Does anyone know anything about low S... - Pernicious Anaemi...

Pernicious Anaemia Society

32,093 members23,240 posts

Does anyone know anything about low SigA levels and links with b12 deficiency please?

Jo5454 profile image
0 Replies

Hi…I’ve recently read an article, but can’t find it at mo! that low SigA levels along with high gastrin levels can indicate b12 deficiency.

It caught my attention as on 2 previous tests, a stool and a saliva test, the SigA was included and very low both times which says can give rise to infections,allergies and autoimmune issues.

I have an allergy that I carry epipens for, a milk intolerance showed on test and just get higher temperatures and become unwell if I reintroduce & often seem to react to things with no particular pattern, constant hayfever,ME diagnosis, thyroid issues on and off, so am wondering if the low SigA is more significant than I’ve realised and whether helping that will help all the other issues. Had never read links with b12 before…has anyone had SigA ever mentioned to them please or investigated it further?

Written by
Jo5454 profile image
Jo5454
To view profiles and participate in discussions please or .
Read more about...

You may also like...

Does anyone in Victoria, Australia know of any doctors who really understand about b12 deficiency?

Most doctors seem reluctant to test for b12 even if there is a family history of pernicious anemia...

NICE CKS link about B12 deficiency symptoms

says symptoms of B12 deficiency can occur without anaemia and without low B12 levels. Could be a...

Frosty Endo Knows Nothing About B12 Deficiency!!

impressed when I asked her to read them but did and took some notes. B12 wasn't the only reason I...

With normal levels of b12 can you still be deficient

and depression, I had blood tests resulting in low folate but b12 levels are normal 420, I seem to...

Low 'normal' B12 and high folate - B12 deficient?

which shows a B12 serum level of 228.0 ng/L (i.e. normal range), a serum folate level of 8.40 ug/L...